“The pain felt during botulinum toxin type-A injections and the troubled and distressed treatment it induces is common and well known for the patient and the doctor applying the treatment.”
— Nedim Sarifakioglu MD, Annuals of Plastic Surgery December 2004

Global 2016 Lip Filler Market: $2.4 billion, CAGR 9.5%
Millennium Research Group 2013

"Performing lip augmentation using fillers is a very common procedure. Yes, it can be painful. I would say 10% don't take any anesthetic. 80% need a topical anesthetic only and about 10% need a nerve block injection." —Wallach MD

Combined aesthetics markets total $US 7+ billion with 9+ million procedures with each procedure involving 3-4 and potentially up to 15 needle sticks. Patients need to repeat procedures every 3-6 months to achieved and maintain best results.